Both the Purosangue and AMG GLE have child safety locks to prevent children from opening the rear doors. The Purosangue has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The AMG GLE’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The Purosangue’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane. A lane departure warning system costs extra on the AMG GLE.
Both the Purosangue and the AMG GLE have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, four-wheel antilock brakes, all-wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available around view monitors.

