The QX65’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The CX-50 doesn’t offer pre-crash pretensioners.
For enhanced safety, the front and rear seat shoulder belts of the Infiniti QX65 are height-adjustable to accommodate a wide variety of driver and passenger heights. A better fit can prevent injuries and the increased comfort also encourages passengers to buckle up. The Mazda CX-50 has only front height-adjustable seat belts.
The QX65 Autograph offers an optional front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The CX-50 doesn’t offer front seat center airbags.
Both the QX65 and the CX-50 have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available around view monitors.
The Infiniti QX65 weighs 655 to 974 pounds more than the Mazda CX-50. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

