The Lexus ES has standard driver and front passenger side knee airbags mounted low on the dashboard. These airbags help prevent the driver and front passenger from sliding under their seatbelts or the main frontal airbags; this keeps them better positioned during a collision for maximum protection. Knee airbags also help keep the legs from striking the dashboard, preventing knee and leg injuries in the case of a serious frontal collision. The E-Class Sedan doesn’t offer a front passenger side knee airbag.
The ES’ standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the E-Class Sedan.
The Lexus ES’ rear backup camera has a standard washer for maintaining a clear view under various conditions. In contrast, the Mercedes E-Class Sedan does not offer a rear camera washer, meaning its effectiveness relies on manual cleaning by the user when necessary.
Both the ES and the E-Class Sedan have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, blind spot warning systems, rearview cameras, rear cross-path warning, available all wheel drive, around view monitors and driver alert monitors.

