Over 200 people are killed each year when backed over by motor vehicles. The AMG GT 4-Door has a standard Rear Cross Traffic Brake that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The RS 5 Sportback doesn’t offer automatic braking for stationary objects directly to the rear.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The AMG GT 4-Door has Car-to-X, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The RS 5 Sportback doesn’t offer a system that can receive automated systems from other vehicles.
The AMG GT 4-Door has a standard blind spot warning system that uses sensors to alert the driver to objects in the vehicle’s blind spots where the side view mirrors don’t reveal them. A system to reveal vehicles in the RS 5 Sportback’s blind spot costs extra.
To help make backing out of a parking space safer, the AMG GT 4-Door has standard Rear Cross-Traffic Alert and Rear Cross Traffic Brake automatically engages the brakes to help avoid a collision. Audi charges extra for Rear Cross-Traffic Assist on the RS 5 Sportback.
The AMG GT 4-Door’s driver alert monitor detects an inattentive driver then sounds a warning and suggests a break. According to the NHTSA, drivers who fall asleep cause about 100,000 crashes and 1500 deaths a year. The RS 5 Sportback doesn’t offer a driver alert monitor.
Both the AMG GT 4-Door and the RS 5 Sportback have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, rearview cameras and available lane departure warning systems.
The Mercedes AMG GT 4-Door weighs 474 to 1190 pounds more than the Audi RS 5 Sportback. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts.

