Both the Defender 110/130 and GLC Coupe have child safety locks to prevent children from opening the rear doors. The Defender has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The GLC Coupe’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The Defender’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the GLC Coupe.
The Land Rover Defender’s rear backup camera has a standard washer for maintaining a clear view under various conditions. In contrast, the Mercedes GLC Coupe does not offer a rear camera washer, meaning its effectiveness relies on manual cleaning by the user when necessary.
Both the Defender and the GLC Coupe have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, front and rear seatbelt pretensioners, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, around view monitors, rear cross-path warning and driver alert monitors.
The Land Rover Defender weighs 542 to 1597 pounds more than the Mercedes GLC Coupe. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

