Compare the2026 Mercedes AMG E-Class WagonVS 2025 Porsche Panamera

In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the AMG E-Class Wagon are reminded to check the back seat if they opened the rear door before starting out. The Panamera doesn’t offer a back seat reminder.

The AMG E-Class Wagon has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The Panamera doesn’t offer front seat center airbags.

The AMG E-Class Wagon has standard whiplash protection, which use a specially designed headrest to protect the driver and front passenger from whiplash. During a rear-end collision, the whiplash protection system moves the headrests forward to prevent neck and spine injuries. The Panamera doesn’t offer a whiplash protection system.

To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the AMG E-Class Wagon. But it costs extra on the Panamera.

Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The AMG E-Class Wagon has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The Panamera doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.

Both the AMG E-Class Wagon and the Panamera have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, post-collision automatic braking systems, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available lane departure warning systems.

There are almost 2 times as many Mercedes dealers as there are Porsche dealers, which makes it much easier should you ever need service under the AMG E-Class Wagon’s warranty.

The AMG E-Class Wagon has more powerful engines than the Panamera:

On the EPA test cycle the AMG E-Class Wagon running on electricity gets better mileage than the Panamera running on electricity:

On the EPA test cycle the AMG E-Class Wagon running its gasoline engine gets better mileage than the Panamera running its gasoline engine:

The AMG E 53 HYBRID Wagon can travel with zero emissions for 41 miles. The Panamera can’t move without running its internal combustion engine.

In its Green Vehicle Guide, the U.S. Environmental Protection Agency (EPA) rates the Mercedes AMG E-Class Wagon higher (6 out of 10) than the Porsche Panamera (4). This means the AMG E-Class Wagon produces up to 12.1 pounds less smog-producing pollutants than the Panamera every 15,000 miles.

A nine-speed automatic is standard on the Mercedes AMG E-Class Wagon, for better acceleration and lower engine speed on the highway. Only an eight-speed automatic is available for the Panamera.

For better stopping power the AMG E-Class Wagon’s standard brake rotors are larger than those on the Panamera:

The AMG E-Class Wagon’s standard 265/40R20 front and 295/35R20 rear tires provide better handling because they have a lower 40 series front and 35 series rear profile (height to width ratio) that provides a stiffer sidewall than the Panamera’s standard 45 series front and 40 series rear tires.

For better ride, handling and brake cooling the AMG E-Class Wagon has standard 20-inch wheels. Smaller 19-inch wheels are standard on the Panamera.

The AMG E-Class Wagon is 3.7 inches shorter than the Panamera, making the AMG E-Class Wagon easier to handle, maneuver and park in tight spaces. The AMG E-Class Wagon is 3.8 inches shorter than the Panamera Turbo E-Hybrid.

Pulling a handle automatically lowers the AMG E-Class Wagon’s rear seats, to make changing between passengers and cargo easier. The Panamera doesn’t offer automatic folding seats.

The AMG E-Class Wagon has a standard remote vehicle starting system, so the vehicle can be started from inside the driver's house. This allows the driver to comfortably warm up the engine before going out to the vehicle. The climate system will also automatically heat or cool the interior. The Panamera doesn’t offer a remote starting system.

If the windows are left open on the AMG E-Class Wagon the driver can close all of them at the outside door handle or from a distance using the remote. On a hot day the driver can lower the windows from a distance using the keyless remote. The driver of the Panamera can only operate the windows from inside the vehicle, with the ignition on.

The AMG E-Class Wagon’s power window, power lock, power mirror and cruise control switches are lit from behind, making them plainly visible and easier to operate at night. The Panamera’s cruise control switches are unlit, making them difficult to find at night and operate safely.

To improve rear visibility by keeping the rear window clear, the AMG E-Class Wagon has a standard rear wiper. The Panamera doesn’t offer a rear wiper.

To shield the driver and front passenger’s vision over a larger portion of the windshield and side windows, the AMG E-Class Wagon has standard extendable sun visors. The Panamera doesn’t offer extendable visors.

The Mercedes AMG E-Class comes in sedan and station wagon bodystyles; the Porsche Panamera isn’t available as a station wagon.

Motor Trend selected the E-Class as their 2025 Car of the Year. The Panamera has never been chosen.