Both the Vistiq and QX60 have child safety locks to prevent children from opening the rear doors. The Vistiq has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The QX60’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
To provide maximum traction and stability on all roads, Full-Time Four-Wheel Drive is standard on the Vistiq. But it costs extra on the QX60.
A passive infrared night vision system standard on the Vistiq Premium Luxury/Platinum helps the driver to more easily detect people, animals or other objects in front of the vehicle at night. Using an infrared camera to detect heat, the system then displays the image on a monitor in the dashboard. The QX60 doesn’t offer a night vision system.
The Cadillac Vistiq’s rear backup camera has a standard washer for maintaining a clear view under various conditions. In contrast, the Infiniti QX60 does not offer a rear camera washer, meaning its effectiveness relies on manual cleaning by the user when necessary.
Both the Vistiq and QX60 have Rear Cross Traffic Alert, but the Vistiq has Rear Cross Traffic Braking (automatically applies the brakes) to better prevent a collision when backing near traffic. The QX60’s Rear Cross Traffic Alert doesn’t automatically brake.
Both the Vistiq and the QX60 have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, front seat center airbag, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras and rear cross-path warning.
The Cadillac Vistiq weighs 1584 to 1787 pounds more than the Infiniti QX60. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

