For enhanced safety, the front and rear seat shoulder belts of the Nissan Murano have pretensioners to tighten the seatbelts and eliminate dangerous slack in the event of a collision and force limiters to limit the pressure the belts will exert on the passengers. The Mazda CX-5 doesn’t offer pretensioners for its rear seat belts.
The Nissan Murano has standard driver and front passenger side knee airbags mounted low on the dashboard. These airbags help prevent the driver and front passenger from sliding under their seatbelts or the main frontal airbags; this keeps them better positioned during a collision for maximum protection. Knee airbags also help keep the legs from striking the dashboard, preventing knee and leg injuries in the case of a serious frontal collision. The CX-5 doesn’t offer knee airbags.
The Murano Platinum offers an optional front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The CX-5 doesn’t offer front seat center airbags.
In a Vehicle-to-Vehicle Frontal Crash Prevention 2.0 test conducted by the Insurance Institute for Highway Safety (IIHS), the Nissan Murano achieved an “Acceptable” rating for its forward collision warning and automatic braking systems, outperforming the Mazda CX-5 which scored “Poor” - the lowest rating - in these critical safety features.
Compared to metal, the Murano’s plastic fuel tank can withstand harder, more intrusive impacts without leaking; this decreases the possibility of fire. The Mazda CX-5 has a metal gas tank.
Both the Murano and the CX-5 have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning and available around view monitors.
The Nissan Murano weighs 419 to 707 pounds more than the Mazda CX-5. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.
The Nissan Murano has achieved the Insurance Institute for Highway Safety’s (IIHS) highest rating of “Top Safety Pick Plus” for the 2026 model year. This distinction is based on its exceptional performance in IIHS’ rigorous battery of safety tests. Specifically, it earned a “Good” rating in the latest, more stringent moderate overlap front crash test, a “Good” result in the updated side impact test, a “Good” score in the revised pedestrian crash prevention test, and an “Acceptable” score in the revised vehicle-to-vehicle crash prevention test. The CX-5 is not even a standard “Top Safety Pick” for 2026.

