Compare the2025 Mercedes E-Class SedanVS 2024 Porsche Panamera

The E-Class Sedan’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The Panamera doesn’t offer pre-crash pretensioners.

In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the E-Class Sedan are reminded to check the back seat if they opened the rear door before starting out. The Panamera doesn’t offer a back seat reminder.

The E-Class Sedan has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The Panamera doesn’t offer front seat center airbags.

The E-Class Sedan offers an optional Post Collision Brake, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Panamera doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.

Over 200 people are killed each year when backed over by motor vehicles. The E-Class Sedan has a standard Maneuvering Brake Function that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The Panamera doesn’t offer automatic braking for stationary objects directly to the rear.

Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The E-Class Sedan has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The Panamera doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.

The E-Class Sedan’s driver alert monitor detects an inattentive driver then sounds a warning and suggests a break. According to the NHTSA, drivers who fall asleep cause about 100,000 crashes and 1500 deaths a year. The Panamera doesn’t offer a driver alert monitor.

Both the E-Class Sedan and the Panamera have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, available all wheel drive and lane departure warning systems.

There are almost 2 times as many Mercedes dealers as there are Porsche dealers, which makes it much easier should you ever need service under the E-Class Sedan’s warranty.

On the EPA test cycle the E-Class Sedan gets better mileage than the Panamera running its gasoline engine:

A nine-speed automatic is standard on the Mercedes E-Class Sedan, for better acceleration and lower engine speed on the highway. Only an eight-speed automatic is available for the Panamera.

The E-Class Sedan stops shorter than the Panamera:

Changing a flat tire near traffic can be dangerous and inconvenient. The run-flat tires available on the E-Class Sedan can be driven up to 50 miles without any air pressure, allowing you to drive to a service station for a repair. The Panamera doesn’t offer run-flat tires.

The E-Class Sedan’s drift compensation steering can automatically compensate for road conditions which would cause the vehicle to drift from side to side, helping the driver to keep the vehicle straight more easily. The Panamera doesn’t offer drift compensation steering.

For better maneuverability, the E-Class Sedan’s turning circle is tighter than the Panamera’s:

The E-Class Sedan is 4 inches shorter than the Panamera, making the E-Class Sedan easier to handle, maneuver and park in tight spaces.

Pressing a switch automatically lowers the E-Class Sedan’s rear seats, to make changing between passengers and cargo easier. The Panamera doesn’t offer automatic folding seats.

With its sedan body style, valet key, locking rear seatbacks and remote trunk release lockout, the E-Class offers cargo security. The Panamera’s hatchback body style, non-lockable folding seat and non-lockable remote release defeat cargo security.

The E-Class Sedan has a standard remote vehicle starting system, so the vehicle can be started from inside the driver's house. This allows the driver to comfortably warm up the engine before going out to the vehicle. The climate system will also automatically heat or cool the interior. The Panamera doesn’t offer a remote starting system.

If the windows are left open on the E-Class Sedan the driver can close them all at the outside door handle or from a distance using the remote. On a hot day the driver can lower the windows from a distance using the keyless remote. The driver of the Panamera can only operate the windows from inside the vehicle, with the ignition on.

The E-Class Sedan’s power window, power lock, power mirror and cruise control switches are lit from behind, making them plainly visible and easier to operate at night. The Panamera’s cruise control switches are unlit, making them difficult to find at night and operate safely.

To shield the driver and front passenger’s vision over a larger portion of the windshield and side windows, the E-Class Sedan has standard extendable sun visors. The Panamera doesn’t offer extendable visors.

The Mercedes E-Class comes in sedan and station wagon bodystyles; the Porsche Panamera isn’t available as a station wagon.

The Mercedes E-Class/CLS outsold the Porsche Panamera by over four to one during 2023.