Compare the2025 Mercedes E-Class SedanVS 2025 Acura TLX

Safety
Warranty
Engine
Fuel Economy and Range
Environmental Friendliness
Transmission
Brakes and Stopping
Tires and Wheels
Suspension and Handling
Passenger Space
Cargo Capacity
Servicing Ease
Ergonomics
Model Availability
Recommendations

Safety

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The E-Class Sedan’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The TLX doesn’t offer pre-crash pretensioners.

In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the E-Class Sedan are reminded to check the back seat if they opened the rear door before starting out. The TLX doesn’t offer a back seat reminder.

The E-Class Sedan has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The TLX doesn’t offer front seat center airbags.

The E-Class Sedan offers an optional Post Collision Brake, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The TLX doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.

Over 200 people are killed each year when backed over by motor vehicles. The E-Class Sedan has a standard Maneuvering Brake Function that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The TLX doesn’t offer backup collision prevention brakes.

Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The E-Class Sedan has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The TLX doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.

Both the E-Class Sedan and TLX have rear cross-traffic warning, but the E-Class Sedan has Active Brake Assist (automatically applies the brakes) to better prevent a collision when backing near traffic. The TLX’s Rear Cross Traffic Monitor doesn’t automatically brake.

Both the E-Class Sedan and the TLX have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available all wheel drive and lane departure warning systems.

Warranty

There are over 41 percent more Mercedes dealers than there are Acura dealers, which makes it easier should you ever need service under the E-Class Sedan’s warranty.

Engine

The E 350 Sedan’s standard 2.0 turbo 4-cylinder hybrid produces 15 lbs.-ft. more torque (295 vs. 280) than the TLX’s standard 2.0 turbo 4-cylinder. The E 450 Sedan’s standard 3.0 turbo 6-cylinder hybrid produces 20 more horsepower (375 vs. 355) and 15 lbs.-ft. more torque (369 vs. 354) than the TLX Type S’ standard 3.0 turbo V6.

As tested in Car and Driver the E 350 Sedan 2.0 turbo 4-cylinder hybrid is faster than the Acura TLX turbo 4 cyl.:

	E-Class Sedan	TLX
Zero to 60 MPH	5.8 sec	5.9 sec
Quarter Mile	14.3 sec	14.5 sec

As tested in Motor Trend the E 450 Sedan 3.0 turbo 6-cylinder hybrid is faster than the TLX Type S 3.0 turbo V6:

	E-Class Sedan	TLX
Zero to 60 MPH	4.7 sec	5.1 sec
Quarter Mile	13.1 sec	13.7 sec
Speed in 1/4 Mile	106.8 MPH	101.8 MPH

Fuel Economy and Range

On the EPA test cycle the E-Class Sedan gets better mileage than the TLX:

			MPG
E-Class Sedan
	AWD	2.0 turbo 4-cyl. Hybrid	24 city/33 hwy
		3.0 turbo 6-cyl. Hybrid	22 city/31 hwy
TLX
	FWD	2.0 turbo 4-cyl.	22 city/31 hwy
	AWD	2.0 turbo 4-cyl.	21 city/29 hwy
		3.0 turbo V6	19 city/25 hwy

Regenerative brakes improve the E-Class Sedan’s fuel efficiency by converting inertia back into energy instead of wasting it. The TLX doesn’t offer a regenerative braking system.

The E-Class Sedan has 1.5 gallons more fuel capacity than the TLX (17.4 vs. 15.9 gallons), for longer range between fill-ups.

Environmental Friendliness

In its Green Vehicle Guide, the U.S. Environmental Protection Agency (EPA) rates the Mercedes E-Class Sedan higher (6 to 7 out of 10) than the Acura TLX (4 to 6). This means the E-Class Sedan produces up to 13.2 pounds less smog-producing pollutants than the TLX every 15,000 miles.

Transmission

The E-Class Sedan’s launch control uses engine electronics to hold engine RPM’s precisely in order to provide the most stable and rapid acceleration possible, using all of the available traction. The TLX doesn’t offer launch control.

Brakes and Stopping

For better stopping power the E-Class Sedan’s front brake rotors are larger than those on the TLX:

	E 350 Sedan	E 450 Sedan	TLX	TLX Type S
Front Rotors	13.5 inches	14.6 inches	13 inches	14.3 inches
Rear Rotors	12.6 inches	14.2 inches	13 inches	13 inches

The E-Class Sedan’s standard front and rear disc brakes are vented to help dissipate heat for shorter stops with less fading. The rear discs on the TLX are solid, not vented.

The E-Class Sedan stops much shorter than the TLX:

	E-Class Sedan	TLX
100 to 0 MPH	305 feet	362 feet	Car and Driver
70 to 0 MPH	150 feet	177 feet	Car and Driver
60 to 0 MPH	104 feet	127 feet	Motor Trend

Tires and Wheels

The E-Class Sedan’s 275/30R21 rear tires provide better handling because they have a lower 30 series profile (height to width ratio) that provides a stiffer sidewall than the TLX Type S’ 35 series tires.

For better ride, handling and brake cooling the E-Class Sedan has standard 21-inch wheels. The TLX’s largest wheels are only 20-inches.

Changing a flat tire near traffic can be dangerous and inconvenient. The run-flat tires available on the E-Class Sedan can be driven up to 50 miles without any air pressure, allowing you to drive to a service station for a repair. The TLX doesn’t offer run-flat tires.

Suspension and Handling

The E-Class Sedan has a standard automatic front and rear load leveling suspension to keep ride height level with a heavy load or when towing. The E-Class Sedan’s height leveling suspension allows the driver to raise ride height for better off-road clearance and then lower it again for easier entering and exiting and better on-road handling. The TLX doesn’t offer a load leveling suspension.

The E-Class Sedan’s drift compensation steering can automatically compensate for road conditions which would cause the vehicle to drift from side to side, helping the driver to keep the vehicle straight more easily. The TLX doesn’t offer drift compensation steering.

For a smoother ride and more stable handling, the E-Class Sedan’s wheelbase is 3.6 inches longer than on the TLX (116.6 inches vs. 113 inches).

The E-Class Sedan’s front to rear weight distribution is more even (54% to 46%) than the TLX’s (57% to 43%). This gives the E-Class Sedan more stable handling and braking.

The E 350 Sedan 4MATIC handles at .93 G’s, while the TLX A-Spec SH-AWD pulls only .87 G’s of cornering force in a Car and Driver skidpad test.

The E 450 Sedan executes Motor Trend’s “Figure Eight” maneuver 1.1 seconds quicker than the TLX A-Spec SH-AWD (25.8 seconds @ .73 average G’s vs. 26.9 seconds @ .64 average G’s).

For better maneuverability, the E 350 Sedan’s turning circle is 2.1 feet tighter than the TLX’s (38.1 feet vs. 40.2 feet). The E 450 Sedan’s turning circle is .8 feet tighter than the TLX’s (39.4 feet vs. 40.2 feet).

Passenger Space

Because it has more passenger and cargo room, the EPA rates the E-Class Sedan a Mid-size car, while the TLX is rated a Compact.

The E-Class Sedan has 6.6 cubic feet more passenger volume than the TLX (100 vs. 93.4).

The E-Class Sedan has .1 inches more front headroom, 1.3 inches more rear headroom, 1.3 inches more rear legroom and 2.1 inches more rear shoulder room than the TLX.

Cargo Capacity

Pressing a switch automatically lowers the E-Class Sedan’s rear seats, to make changing between passengers and cargo easier. The TLX doesn’t offer automatic folding seats.

To make loading and unloading groceries and cargo easier when your hands are full, the E-Class Sedan’s power trunk can be opened or closed just by kicking your foot under the back bumper, leaving your hands completely free. The TLX doesn’t offer a power or hands-free opening trunk.

Servicing Ease

The engine in the E-Class Sedan is mounted longitudinally (North-South), instead of sideways, as in the TLX. This makes it easier to service and maintain, because there are no rear spark plugs and the accessory belts are in front.

Ergonomics

Unlike the driver-only memory seat and mirrors in the TLX, the E-Class Sedan has standard driver and passenger memory, so that when drivers switch, the memory setting adjusts the driver’s seat, steering wheel position and outside mirror angle and the front passenger seat also adjusts to the new passenger’s preset preferences.

The power windows standard on both the E-Class Sedan and the TLX have locks to prevent small children from operating them. When the lock on the E-Class Sedan is engaged the driver can still operate all of the windows, for instance to close one opened by a child. The TLX prevents the driver from operating the other windows just as it does the other passengers.

The E-Class Sedan’s standard Keyless-Go allow you to unlock the doors from any outside door handle, open the trunk, and start the engine, all without removing the key from the pocket or purse. Smart Entry standard on the TLX doesn’t offer a sensor on the rear doors, so you’ll have to reach a front handle to unlock the rear door.

The E-Class Sedan’s rain-sensitive wipers adjust their speed and turn on and off automatically based on the amount of rainfall on the windshield. This allows the driver to concentrate on driving without constantly adjusting the wipers. The TLX’s standard intermittent wipers change speed with vehicle speed, but can’t turn on and off or change speed based on changing rainfall.

Heated windshield washer nozzles are optional on the E-Class Sedan to prevent washer fluid and nozzles from freezing and help continue to keep the windshield clear in sub-freezing temperatures. The TLX doesn’t offer heated windshield washer nozzles.

To help drivers avoid possible obstacles, the E-Class Sedan offers optional cornering lights to illuminate around corners when the turn signals are activated. The TLX doesn’t offer cornering lights. The E-Class Sedan also offers optional adaptive headlights to illuminate around corners automatically by reading vehicle speed and steering wheel angle.

A power rear sunshade and manual rear side window sunshades are optional in the E-Class Sedan to help block heat and glare for the rear passengers. The TLX doesn’t offer a rear or rear side window sunshades.

The E-Class Sedan’s standard rear and side view mirrors have an automatic dimming feature. These mirrors can be set to automatically darken quickly when headlights shine on them, keeping following vehicles from blinding or distracting the driver. The TLX has an automatic rear view mirror, but its side mirrors don’t dim.

The Mercedes E-Class Sedan has power folding mirrors that offer unparalleled convenience while maneuvering in tight places or parked. With the mirrors folded it’s easier to walk past and help prevent parking damage. The mirrors can be quickly unfolded when the driver is ready to leave. Power folding mirrors are only offered on the TLX Type S.

Both the E-Class Sedan and the TLX have standard heated front seats. The E-Class Sedan also offers optional heated rear seats to keep those passengers extremely comfortable in the winter. Heated rear seats aren’t available in the TLX.

The E-Class Sedan offers optional massaging front seats in order to maximize comfort and eliminate fatigue on long trips. Massaging seats aren’t available in the TLX.

The E-Class Sedan’s Active Parking Assist can parallel park or back into a parking spot by itself, starting, stopping and changing direction automatically. Remote Parking Assist will park and retrieve your car remotely: press a button and watch it park itself. This is ideal for tight locations. The TLX doesn’t offer an automated parking system.

Model Availability

The Mercedes E-Class comes in sedan and station wagon bodystyles; the Acura TLX isn’t available as a station wagon.

Recommendations

The Mercedes E-Class/CLS outsold the Acura TLX by 344 units during 2023.