Compare the2025 Mercedes AMG E-Class SedanVS 2024 Audi S6

The AMG E-Class Sedan has a standard front seat center airbag, which deploys between the driver and front passenger, protecting them from injuries caused by striking each other in serious side impacts. The S6 doesn’t offer front seat center airbags.

Over 200 people are killed each year when backed over by motor vehicles. The AMG E-Class Sedan has a standard Maneuvering Brake Function that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The S6 doesn’t offer automatic braking for stationary objects directly to the rear.

The AMG E-Class Sedan has a standard blind spot warning system that uses sensors to alert the driver to objects in the vehicle’s blind spots where the side view mirrors don’t reveal them. A system to reveal vehicles in the S6’s blind spot costs extra.

To help make backing out of a parking space safer, the AMG E-Class Sedan has standard Rear Cross-Traffic Alert and Active Brake Assist automatically engages the brakes to help avoid a collision. Audi charges extra for Rear Cross-Traffic Assist on the S6.

The AMG E-Class Sedan’s driver alert monitor detects an inattentive driver then sounds a warning and suggests a break. According to the NHTSA, drivers who fall asleep cause about 100,000 crashes and 1500 deaths a year. The S6 doesn’t offer a driver alert monitor.

Both the AMG E-Class Sedan and the S6 have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, rearview cameras and available lane departure warning systems.

There are over 25 percent more Mercedes dealers than there are Audi dealers, which makes it easier should you ever need service under the AMG E-Class Sedan’s warranty.

J.D. Power and Associates’ 2024 Initial Quality Study of new car owners surveyed provide the statistics that show that Mercedes vehicles are better in initial quality than Audi vehicles. With 36 fewer problems per 100 vehicles, JD Power ranks Mercedes higher than Audi.

J.D. Power and Associates’ 2024 survey of the owners of three-year-old vehicles provides the long-term dependability statistics that show that Mercedes vehicles are more reliable than Audi With 57 fewer problems per 100 vehicles in the first three years of ownership, J.D. Power ranks Mercedes higher than Audi.

The AMG E 53 HYBRID Sedan’s standard 3.0 turbo 6-cylinder hybrid produces 133 more horsepower (577 vs. 444) and 111 lbs.-ft. more torque (553 vs. 442) than the S6’s 2.9 turbo V6 hybrid. The AMG E 53 HYBRID Sedan’s optional 3.0 turbo 6-cylinder hybrid produces 160 more horsepower (604 vs. 444) and 111 lbs.-ft. more torque (553 vs. 442) than the S6’s 2.9 turbo V6 hybrid.

On the EPA test cycle the AMG E 53 HYBRID Sedan running on electricity gets better mileage than the S6 (54 city/65 hwy MPGe vs. 19 city/26 hwy).

The AMG E 53 HYBRID Sedan can travel with zero emissions for 42 miles. The S6 can’t move without running its internal combustion engine.

A nine-speed automatic is standard on the Mercedes AMG E-Class Sedan, for better acceleration and lower engine speed on the highway. Only an eight-speed automatic is available for the S6.

The AMG E-Class Sedan’s optional launch control uses engine electronics to hold engine RPM’s precisely in order to provide the most stable and rapid acceleration possible, using all of the available traction. The S6 doesn’t offer launch control.

For better traction, the AMG E-Class Sedan has larger tires than the S6 (F:265/40R20 & R:295/35R20 vs. 255/35R21).

The AMG E-Class Sedan’s optional 295/30R21 rear tires provide better handling because they have a lower 30 series profile (height to width ratio) that provides a stiffer sidewall than the S6’s 35 series tires.

For a smoother ride and more stable handling, the AMG E-Class Sedan’s wheelbase is 1.3 inches longer than on the S6 (116.6 inches vs. 115.3 inches).

For better maneuverability, the AMG E-Class Sedan’s turning circle is 1 foot tighter than the S6’s (38.7 feet vs. 39.7 feet).

The Mercedes AMG E-Class Sedan may be more efficient, handle and accelerate better because it weighs about 250 pounds less than the Audi S6.

The AMG E-Class Sedan has .2 inches more front legroom and .6 inches more rear shoulder room than the S6.

Pressing a switch automatically lowers the AMG E-Class Sedan’s rear seats, to make changing between passengers and cargo easier. The S6 doesn’t offer automatic folding seats.

To quickly and conveniently keep personal devices charged without cables tangling and wearing out, the Mercedes AMG E-Class has a standard wireless phone charging system (Qi) in the center console. Wireless charging costs extra on the S6.

The Mercedes AMG E-Class comes in sedan and station wagon bodystyles; the Audi S6 isn’t available as a station wagon.

The Mercedes E-Class/CLS outsold the Audi A6/S6/RS 6 by over two to one during 2023.