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For better traction, the QX55 has larger tires than the RX (255/45R20 vs. 235/60R19).
The QX55’s tires provide better handling because they have a lower 45 series profile (height to width ratio) that provides a stiffer sidewall than the RX’s standard 60 series tires. The QX55’s tires are lower profile than the RX’s optional 50 series tires.
For better ride, handling and brake cooling the QX55 has standard 20-inch wheels. Smaller 19-inch wheels are standard on the RX.
The QX55 has a standard easy tire fill system. When inflating the tires, the vehicle’s integrated tire pressure sensors keep track of the pressure as the tires fill and tell the driver when the tires are inflated to the proper pressure. The RX doesn’t offer vehicle monitored tire inflation.
Changing a flat tire near traffic can be dangerous and inconvenient. The run-flat tires standard on the QX55 can be driven up to 50 miles without any air pressure, allowing you to drive to a service station for a repair. The RX doesn’t offer run-flat tires.