The AMG S-Class’ pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The Panamera doesn’t offer pre-crash pretensioners.
The rear seatbelts optional on the AMG S-Class inflate when a collision is detected, helping to spread crash forces over a much larger area of the body and limiting head and neck movement. This can help prevent spinal and internal injuries. The Panamera doesn’t offer inflatable seatbelts.
The AMG S-Class has standard Post-Collision Brake, which automatically apply the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Panamera doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
Over 200 people are killed each year when backed over by motor vehicles. The AMG S-Class has a standard Maneuvering Brake that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The Panamera doesn’t offer automatic braking for stationary objects directly to the rear.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the AMG S-Class. But it costs extra on the Panamera.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The AMG S-Class has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The Panamera doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.
The AMG S-Class’ driver alert monitor detects an inattentive driver then sounds a warning and suggests a break. According to the NHTSA, drivers who fall asleep cause about 100,000 crashes and 1500 deaths a year. The Panamera doesn’t offer a driver alert monitor.
Both the AMG S-Class and the Panamera have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras and rear cross-path warning.
The Mercedes AMG S-Class weighs 418 to 1425 pounds more than the Porsche Panamera. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts.