The E-Class Sedan’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The ES doesn’t offer pre-crash pretensioners.
In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the E-Class Sedan are reminded to check the back seat if they opened the rear door before starting out. The ES doesn’t offer a back seat reminder.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the E-Class Sedan. But it costs extra on the ES.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The E-Class Sedan has Car-to-X Communication, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The ES doesn’t offer a system that can receive automated systems from infrastructure or other vehicles.
To help make backing out of a parking space safer, the E-Class Sedan has standard Rear Cross-Traffic Alert with Active Brake Assist, systems which detect vehicles approaching from the sides and can automatically apply the brakes to prevent a collision. Rear Cross-Traffic Braking costs extra on the ES.
Both the E-Class Sedan and the ES have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors and available lane departure warning systems.
The Mercedes E-Class Sedan weighs 409 to 686 pounds more than the Lexus ES. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts.