The S6’s pre-crash front seatbelts will tighten automatically in the event the vehicle detects an impending crash, improving protection against injury significantly. The Panamera doesn’t offer pre-crash pretensioners.
The S6 has a standard Secondary Collision Brake Assist, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Panamera doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the S6. But it costs extra on the Panamera.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The S6 has Car-to-X Services, a system that seemlesly communicates important warnings to the driver about impending danger, if they're available. The Panamera doesn’t offer a system that can receive automated systems from infrastructure.
To help make backing out of a parking space safer, the S6’s optional Rear Cross-Traffic Assist uses sensors in the rear to alert the driver to vehicles approaching from the side and Automatic Brake Activation automatically engages the brakes to help avoid a collision. The Panamera doesn’t offer a rear cross-path warning system.
Both the S6 and the Panamera have standard driver and passenger frontal airbags, front and rear side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, daytime running lights, lane departure warning systems, rearview cameras, available night vision systems, blind spot warning systems and around view monitors.