In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the Prologue are reminded to check the back seat if they opened the rear door before starting out. The ZDX doesn’t offer a back seat reminder.
The Prologue has standard Collision Mitigation Braking System, which use forward mounted sensors to detect an immediately impending crash (warning the driver first if the available collision warning system is equipped) and automatically apply the brakes at full-force in order to reduce the force of the crash or avoid it altogether. The ZDX doesn't offer collision warning or crash mitigation brakes.
Over 200 people are killed each year when backed over by motor vehicles. The Prologue has standard Reverse Automatic Braking that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The ZDX doesn’t offer automatic braking for stationary objects directly to the rear.
The Prologue’s lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. The ZDX doesn’t offer a lane departure warning system.
The Prologue Elite has a standard Surround Vision System to allow the driver to see objects all around the vehicle on a screen. The ZDX doesn’t offer any parking assist system.
Both the Prologue and the ZDX have standard driver and passenger frontal airbags, four-wheel antilock brakes, traction control, daytime running lights, blind spot warning systems and rear cross-path warning.