The Quattroporte has standard whiplash protection, which use a specially designed headrest to protect the driver and front passenger from whiplash. During a rear-end collision, the whiplash protection system moves the headrests forward to prevent neck and spine injuries. The CLS doesn’t offer a whiplash protection system.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the Quattroporte. But it costs extra on the CLS.
The Quattroporte’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the CLS.
To help make backing out of a parking space safer, the Quattroporte has standard Rear Cross Path, helping the driver avoid collisions. Mercedes charges extra for Rear Cross-Traffic Alert on the CLS.
Both the Quattroporte and the CLS have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems and rearview cameras.

