Both the SQ8 and AMG GLC Coupe have child safety locks to prevent children from opening the rear doors. The SQ8 has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The AMG GLC Coupe’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
When descending a steep, off-road slope, the SQ8’s standard Hill Descent Assist allows you to creep down safely. The AMG GLC Coupe doesn’t offer Hill Descent Assist.
Earlier warning of stopped traffic, traffic signals, dangerous road conditions, weather, or accidents, can keep driver's safer and prevent crashes. The SQ8 has Car-to-X Services, a system that seamlessly communicates important warnings to the driver about impending danger, if they're available. The AMG GLC Coupe doesn’t offer a system that can receive automated systems from infrastructure.
A passive infrared night vision system optional on the SQ8 Prestige helps the driver to more easily detect people, animals or other objects in front of the vehicle at night. Using an infrared camera to detect heat, the system then displays the image on a monitor in the dashboard. The AMG GLC Coupe doesn’t offer a night vision system.
The SQ8’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the AMG GLC Coupe.
Both the SQ8 and the AMG GLC Coupe have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, around view monitors and rear cross-path warning.
The Audi SQ8 weighs 981 pounds more than the Mercedes AMG GLC Coupe. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.
For its top level performance in IIHS driver and passenger-side small overlap frontal, moderate overlap frontal, side impact, roof strength and head restraint tests, its standard vehicle-to-vehicle front crash prevention system, its standard vehicle-to-pedestrian front crash prevention system, and its standard headlight’s “Acceptable” rating, the Insurance Institute for Highway Safety grants the SQ8 its highest rating: “Top Safety Pick Plus” for 2022, a rating granted to only 131 vehicles tested by the IIHS. The AMG GLC Coupe has not been tested, yet.