Both the SQ7 and AMG GLS have child safety locks to prevent children from opening the rear doors. The SQ7 has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The AMG GLS’ child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
A passive infrared night vision system optional on the SQ7 Prestige helps the driver to more easily detect people, animals or other objects in front of the vehicle at night. Using an infrared camera to detect heat, the system then displays the image on a monitor in the dashboard. The AMG GLS doesn’t offer a night vision system.
Both the SQ7 and the AMG GLS have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, post-collision automatic braking systems, daytime running lights, lane departure warning systems, blind spot warning systems, around view monitors and rear cross-path warning.

