For enhanced safety, the front and rear seat shoulder belts of the Audi S5 Sportback have pretensioners to tighten the seatbelts and eliminate dangerous slack in the event of a collision and force limiters to limit the pressure the belts will exert on the passengers. The Cadillac CT5-V doesn’t offer pretensioners for its rear seat belts.
Both the S5 Sportback and CT5-V have child safety locks to prevent children from opening the rear doors. The S5 Sportback has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The CT5-V’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The S5 Sportback’s standard pretensioning seatbelts also sense rear collisions and remove slack from the seatbelts to help protect the occupants from whiplash and other injuries. The CT5-V doesn’t offer a whiplash protection system.
The S5 Sportback has a standard Secondary Collision Brake Assist, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The CT5-V doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the S5 Sportback. But it costs extra on the CT5-V.
Both the S5 Sportback and CT5-V offer rear cross-traffic warning, but the S5 Sportback with Rear Cross-Traffic Assist also has Automatic Brake Activation (automatically applies the brakes) to better prevent a collision when backing near traffic. The CT5-V’s Rear Cross Traffic Alert doesn’t automatically brake.
Both the S5 Sportback and the CT5-V have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, rearview cameras, available blind spot warning systems and around view monitors.
For its top level performance in IIHS driver and passenger-side small overlap frontal, moderate overlap frontal, side impact, roof strength and head restraint tests, its standard vehicle-to-vehicle front crash prevention system, its standard vehicle-to-pedestrian front crash prevention system, and its available headlight’s “Good” rating, the Insurance Institute for Highway Safety grants the S5 Sportback the rating of “Top Safety Pick” for 2022, a rating granted to only 174 vehicles tested by the IIHS. The CT5-V has not been tested, yet.