Over 200 people are killed each year when backed over by motor vehicles. The QX80 has standard Backup Collision Intervention that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The GX doesn’t offer backup collision prevention brakes.
Both the QX80 and GX have rear cross-traffic warning, but the QX80 has Back-up Collision Intervention (automatically applies the brakes) to better prevent a collision when backing near traffic. The GX’s Rear Cross-Traffic Alert doesn’t automatically brake.
Both the QX80 and the GX have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning and available all wheel drive.
The Infiniti QX80 weighs 509 to 959 pounds more than the Lexus GX. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

