Over 200 people are killed each year when backed over by motor vehicles. The M5 offers an optional Active Park Distance Control that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The RS 6 doesn’t offer backup collision prevention brakes.
The M5 has a standard blind spot warning system that uses sensors to alert the driver to objects in the vehicle’s blind spots where the side view mirrors don’t reveal them. A system to reveal vehicles in the RS 6’s blind spot costs extra.
To help make backing out of a parking space safer, the M5 has standard Cross Traffic Warning, helping the driver avoid collisions. Audi charges extra for rear cross-path warning on the RS 6.
The M5’s driver alert monitor detects an inattentive driver then sounds a warning and suggests a break. According to the NHTSA, drivers who fall asleep cause about 100,000 crashes and 1500 deaths a year. The RS 6 doesn’t offer a driver alert monitor.
Both the M5 and the RS 6 have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, post-collision automatic braking systems, daytime running lights, lane departure warning systems, rearview cameras and available around view monitors.

