Both the CT4 and TLX have child safety locks to prevent children from opening the rear doors. The CT4 has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The TLX’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the CT4 are reminded to check the back seat if they opened the rear door before starting out. The TLX doesn’t offer a back seat reminder.
The CT4’s standard pretensioning seatbelts also sense rear collisions and remove slack from the front seatbelts to help protect the occupants from whiplash and other injuries. The TLX doesn’t offer a whiplash protection system.
Over 200 people are killed each year when backed over by motor vehicles. The CT4 Premium Luxury/Sport has standard Reverse Automatic Braking that uses rear sensors to monitor for objects to the rear and automatically applies the brakes to prevent a collision. The TLX doesn’t offer backup collision prevention brakes.
The CT4 has a standard blind spot warning system that uses sensors to alert the driver to objects in the vehicle’s blind spots where the side view mirrors don’t reveal them. A system to reveal vehicles in the TLX’s blind spot costs extra.
To help make backing out of a parking space safer, the CT4 has standard Rear Cross Traffic Alert, helping the driver avoid collisions. Acura charges extra for Rear Cross Traffic Monitor on the TLX.
Both the CT4 and the TLX have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, rearview cameras, available all wheel drive and around view monitors.