To provide maximum traction and stability on all roads, All-Wheel Drive is standard on the CX-9. But it costs extra on the QX60.
Both the CX-9 and the QX60 have standard driver and passenger frontal airbags, front side-impact airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, available around view monitors and driver alert monitors.
Side impacts caused 23% of all road fatalities in 2018, down from 29% in 2003, when the Insurance Institute for Highway Safety introduced its side barrier test. In order to continue improving vehicle safety, the IIHS has started using a more severe side impact test: 37 MPH (up from 31 MPH), with a 4180-pound barrier (up from 3300 pounds). The results of this newly developed test demonstrates that the Mazda CX-9 is safer than the QX60:
| 
 | CX-9 | QX60 | 
| Overall Evaluation | GOOD | GOOD | 
| Structure | GOOD | ACCEPTABLE | 
| 
 | Driver Injury Measures | |
| Head/Neck | GOOD | GOOD | 
| Head Injury Criterion | 106 | 125 | 
| Neck Tension | 223 lbs. | 268 lbs. | 
| Torso | GOOD | GOOD | 
| Torso Deflection Rate | 5 MPH | 5 MPH | 
| Pelvis | GOOD | MARGINAL | 
| Pelvis Force | 647 lbs. | 1160 lbs. | 
| Head Protection | GOOD | GOOD | 
| 
 | Passenger Injury Measures | |
| Head/Neck | GOOD | GOOD | 
| Torso | GOOD | GOOD | 
| Pelvis | GOOD | GOOD | 
| Head Protection | GOOD | GOOD | 

