For enhanced safety, the front seat shoulder belts of the Porsche Panamera are height-adjustable to accommodate a wide variety of driver and passenger heights. A better fit can prevent injuries and the increased comfort also encourages passengers to buckle up. The Alfa Romeo Giulia Quadrifoglio doesn’t offer height-adjustable seat belts.
Both the Panamera and Giulia Quadrifoglio have child safety locks to prevent children from opening the rear doors. The Panamera has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The Giulia Quadrifoglio’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The Panamera offers all-wheel drive to maximize traction under poor conditions, especially in ice and snow. The Giulia Quadrifoglio doesn’t offer all-wheel drive.
A passive infrared night vision system optional on the Panamera helps the driver to more easily detect people, animals or other objects in front of the vehicle at night. Using an infrared camera to detect heat, the system then displays the image on a monitor in the dashboard and even aims one of the vehicle’s headlights in the direction of the person or object. The Giulia Quadrifoglio doesn’t offer a night vision system.
The Panamera offers an optional Surround View System to allow the driver to see objects all around the vehicle on a screen. The Giulia Quadrifoglio only offers a rear monitor and front and rear parking sensors that beep or flash a light. That doesn’t help with obstacles to the sides.
Both the Panamera and the Giulia Quadrifoglio have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, daytime running lights, lane departure warning systems, rearview cameras, available crash mitigating brakes and blind spot warning systems.
The Porsche Panamera weighs 416 to 1606 pounds more than the Alfa Romeo Giulia Quadrifoglio. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts.