Both the Telluride and GLS have child safety locks to prevent children from opening the rear doors. The Telluride has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The GLS’ child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the Telluride are reminded to check the back seat when a sensor determines the back seat is occupied. The GLS doesn’t offer a back seat reminder.
Over 200 people are killed each year when backed over by motor vehicles. The Telluride SX has standard Parking Collision-Avoidance Assist - Reverse that uses rear sensors to monitor and automatically apply the brakes to prevent a rear collision. The GLS doesn’t offer backup collision prevention brakes.
The Telluride’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the GLS.
Both the Telluride and the GLS have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available all wheel drive and around view monitors.
For its top level performance in IIHS driver and passenger-side small overlap frontal, moderate overlap frontal, side impact, roof strength and head restraint tests, its standard vehicle-to-vehicle front crash prevention system, its standard vehicle-to-pedestrian front crash prevention system, and its available headlight’s “Acceptable” rating, the Insurance Institute for Highway Safety grants the Telluride the rating of “Top Safety Pick” for 2022, a rating granted to only 164 vehicles tested by the IIHS. The GLS has not been tested, yet.