Compare the2022 Lexus RXVS 2022 Mercedes E-Class All-Terrain Wagon

The Lexus RX has standard driver and front passenger side knee airbags mounted low on the dashboard. These airbags helps prevent the driver and front passenger from sliding under their seatbelts or the main frontal airbags; this keeps them better positioned during a collision for maximum protection. Knee airbags also help keep the legs from striking the dashboard, preventing knee and leg injuries in the case of a serious frontal collision. The E-Class All-Terrain Wagon doesn’t offer a front passenger side knee airbag.

The RX has standard Active Headrests, which use a specially designed headrest to protect the driver and front passenger from whiplash. During a rear-end collision, the Active Headrests system moves the headrests forward to prevent neck and spine injuries. The E-Class All-Terrain Wagon doesn’t offer a whiplash protection system.

Over 200 people are killed each year when backed over by motor vehicles. The RX offers optional Auto Brake that uses rear sensors to monitor and automatically apply the brakes to prevent a rear collision. The E-Class All-Terrain Wagon doesn’t offer backup collision prevention brakes.

The RX’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the E-Class All-Terrain Wagon.

To help make backing out of a parking space safer, the RX has a standard rear cross-path warning system, which uses sensors in the rear bumper to alert the driver to vehicles approaching from the side, helping the driver avoid collisions. Rear cross-path warning costs extra on the E-Class All-Terrain Wagon.

Both the RX and the E-Class All-Terrain Wagon have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems, rearview cameras, driver alert monitors, available all wheel drive and around view monitors.

The National Highway Traffic Safety Administration does side impact tests on new vehicles. In this test, which crashes the vehicle into a flat barrier at 38.5 MPH and into a post at 20 MPH, results indicate that the Lexus RX is safer than the Mercedes E-Class All-Terrain Wagon:

New test not comparable to pre-2011 test results. More stars = Better. Lower test results = Better.

For its top level performance in IIHS driver and passenger-side small overlap frontal, moderate overlap frontal, side impact, roof strength and head restraint tests, its standard vehicle-to-vehicle front crash prevention system, its standard vehicle-to-pedestrian front crash prevention system, and its available headlight’s “Acceptable” rating, the Insurance Institute for Highway Safety grants the RX the rating of “Top Safety Pick” for 2021, a rating granted to only 145 vehicles tested by the IIHS. The E-Class All-Terrain Wagon has not been tested, yet.

Lexus’ powertrain warranty covers the RX 2 years and 20,000 miles longer than Mercedes covers the E-Class All-Terrain Wagon. Any repair needed on the engine, transmission, axles, joints or driveshafts is fully covered for 6 years or 70,000 miles. Coverage on the E-Class All-Terrain Wagon ends after only 4 years or 50,000 miles.

The RX’s corrosion warranty is 1 year longer than the E-Class All-Terrain Wagon’s (6 vs. 5 years).

A reliable vehicle saves its owner time, money and trouble. Nobody wants to be stranded or have to be without a vehicle while it’s being repaired. Consumer Reports rates the RX’s reliability 43 points higher than the E-Class All-Terrain Wagon.

J.D. Power and Associates rated the RX first among midsize premium SUVs in their 2021 Initial Quality Study. The E-Class All-Terrain Wagon isn’t in the top three in its category.

J.D. Power and Associates’ 2021 Initial Quality Study of new car owners surveyed provide the statistics that show that Lexus vehicles are better in initial quality than Mercedes vehicles. J.D. Power ranks Lexus third in initial quality, above the industry average. With 49 more problems per 100 vehicles, Mercedes is ranked 25th, below the industry average.

J.D. Power and Associates’ 2021 survey of the owners of three-year-old vehicles provides the long-term dependability statistics that show that Lexus vehicles are more reliable than Mercedes vehicles. J.D. Power ranks Lexus first in reliability, above the industry average. With 41 more problems per 100 vehicles, Mercedes is ranked 15th.

From surveys of all its subscribers, Consumer Reports’ January 2021 Auto Issue reports that Lexus vehicles are more reliable than Mercedes vehicles. Consumer Reports ranks Lexus third in reliability. Mercedes is ranked 20th.

The U.S. Environmental Protection Agency (EPA) certifies the Lexus RX at emission levels ranging from “Ultra Low Emissions Vehicle” (ULEV) to “Super Ultra Low Emissions Vehicle” (SULEV). The Mercedes E-Class All-Terrain Wagon is only certified to “Ultra Low Emissions Vehicle” (ULEV) standards.

The RX 450h has a standard continuously variable transmission (CVT). With no “steps” between gears, it can keep the engine at the most efficient speed for fuel economy, or keep it at its peak horsepower indefinitely for maximum acceleration. The E-Class All-Terrain Wagon doesn’t offer a CVT.

The RX has a standard space-saver spare tire so you can replace a flat tire and drive to have the flat repaired or replaced. A spare tire isn’t available on the E-Class All-Terrain Wagon; it requires you to depend on its run-flat tires, which limits mileage and speed before they are repaired. If a run-flat is damaged beyond repair by a road hazard your vehicle will have to be towed. Some tire options on the E-Class All-Terrain Wagon don’t have a run-flat feature, either.

For greater off-road capability the RX has a 2.45 inches greater minimum ground clearance than the E-Class All-Terrain Wagon (8.2 vs. 5.75 inches), allowing the RX to travel over rougher terrain without being stopped or damaged.

The Lexus RX may be more efficient, handle and accelerate better because it weighs up to about 350 pounds less than the Mercedes E-Class All-Terrain Wagon.

To almost totally eliminate engine vibration in the passenger area, the RX has an electronically controlled liquid-filled front engine mount. A computer-controlled electric current in the liquid changes its viscosity, allowing the mount to dampen the engine completely at all RPMs. The E-Class All-Terrain Wagon uses conventional solid rubber engine mounts.

The RX has 1.9 inches more front headroom, 2.4 inches more front legroom, .9 inches more rear headroom, 1.9 inches more rear legroom and .5 inches more rear shoulder room than the E-Class All-Terrain Wagon.

For enhanced passenger comfort on long trips the RX’s rear seats recline. The E-Class All-Terrain Wagon’s middle row seats don’t recline.

Optional Trailer Sway Control on the RX uses the Vehicle Stability Control sensors to detect trailer sway, then uses individual brakes to counteract any swaying and help keep the tow vehicle and trailer steady. The E-Class All-Terrain Wagon doesn’t offer electronic trailer sway control.

J.D. Power and Associates surveys of service recipients show that Lexus service is better than Mercedes. J.D. Power ranks Lexus second in service department satisfaction. With a 28% lower rating, Mercedes is ranked 6th.

The RX’s power parking brake sets with one touch and releases with one touch or automatically. The E-Class All-Terrain Wagon’s parking brake has to be released manually.

To improve rear visibility by keeping the rear window clear, the RX has a standard rear fixed intermittent wiper with a full on position. The rear wiper standard on the E-Class All-Terrain Wagon only has an intermittent setting, so in a hard rain visibility isn’t as good.

The RX is available in both front-wheel drive and four-wheel drive configurations. The E-Class All-Terrain Wagon doesn’t offer a two-wheel drive configuration.

Insurance will cost less for the RX owner. The Complete Car Cost Guide estimates that insurance for the RX will cost $2880 to $5995 less than the E-Class All-Terrain Wagon over a five-year period.

The RX will cost the buyer less in the long run because of its superior resale value. The IntelliChoice estimates that the RX will retain 57.1% to 58.62% of its original price after five years, while the E-Class All-Terrain Wagon only retains 50.3%.

According to The Car Book by Jack Gillis, the RX is less expensive to operate than the E-Class All-Terrain Wagon because it costs $118 less to do the manufacturer’s suggested maintenance for 50,000 miles. Typical repairs cost much less on the RX than the E-Class All-Terrain Wagon, including $453 less for a muffler, $115 less for a starter, $211 less for fuel injection, $24 less for a fuel pump and $171 less for front struts.

IntelliChoice estimates that five-year ownership costs (depreciation, financing, insurance, fuel, fees, repairs and maintenance) for the Lexus RX will be $21551 to $29274 less than for the Mercedes E-Class All-Terrain Wagon.

Consumer Reports® chose the Lexus RX as its “Top Pick,” the highest scoring vehicle in its category, based on reliability, safety and performance.

The Lexus RX outsold the Mercedes E-Class/CLS by almost five to one during the 2021 model year.