Both the Palisade and RXL have child safety locks to prevent children from opening the rear doors. The Palisade has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The RXL’s child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the Palisade are reminded to check the back seat if they opened the rear door before starting out. The RXL doesn’t offer a back seat reminder.
Both the Palisade and the RXL have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, front wheel drive, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available all wheel drive and around view monitors.
For its top level performance in IIHS driver and passenger-side small overlap frontal, moderate overlap frontal, side impact, roof strength and head restraint tests, its standard vehicle-to-vehicle front crash prevention system, with its optional vehicle-to-pedestrian front crash prevention system, and its standard headlight’s “Good” rating, the Insurance Institute for Highway Safety grants the Palisade its highest rating: “Top Pick Plus” for 2021, a rating granted to only 63 vehicles tested by the IIHS. The RXL is only a standard “Top Pick” for 2021.